Description

1-[(4-Nitrophenyl)Sulfonyl]Tetrahydro-4(1H)-Pyridinone is a specialized sulfonamide derivative featuring a tetrahydro-4(1H)-pyridinone scaffold. This compound is valued as a key synthetic intermediate and building block in advanced organic synthesis, particularly for the development of novel pharmacologically active molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of potential drug candidates, especially those targeting enzymes or receptors where the sulfonamide and lactam moieties are critical for bioactivity.
• Medicinal Chemistry Research: Used in high-throughput screening libraries and structure-activity relationship (SAR) studies to explore new chemical spaces for therapeutic applications.
• Organic Synthesis Reagent: Acts as a versatile precursor for constructing more complex nitrogen- and sulfur-containing heterocycles through further functionalization of the pyridinone ring or the sulfonyl group.
• Agrochemical Development: Employed in research for creating novel active ingredients for crop protection, leveraging its unique structural features.
• Chemical Biology Probes: Can be utilized in the design and synthesis of molecular probes to study biological pathways and protein functions.

Basic Information

Product Name	1-[(4-Nitrophenyl)Sulfonyl]Tetrahydro-4(1H)-Pyridinone
CAS No.	924869-20-5
Molecular Formula	C11H12N2O5S
Molecular Weight	284.29 g/mol
Synonyms	4-(4-Nitrobenzenesulfonyl)tetrahydro-2H-pyridin-4(1H)-one; 1-(4-Nitrobenzenesulfonyl)-4-piperidone; 4-(4-Nitrophenylsulfonyl)-1,2,3,6-tetrahydropyridin-4-ol (tautomer); 4-Piperidone, 1-[(4-nitrophenyl)sulfonyl]-; N-(4-Nitrophenylsulfonyl)-4-piperidone; 1-(4-Nitro-phenylsulfonyl)-piperidin-4-one; 924869-20-5; 1-(4-Nitrobenzenesulfonyl)piperidin-4-one
EINECS	Contact for details

Quality Control

Our 1-[(4-Nitrophenyl)Sulfonyl]Tetrahydro-4(1H)-Pyridinone is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can support development projects requiring material for pre-clinical studies.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.