Description

Methyl 2-Bromo-5-(Chlorosulfonyl)Benzoate is a high-value, multi-functional organic intermediate characterized by its reactive bromine and chlorosulfonyl groups. This compound matters for its role as a critical building block in the synthesis of complex molecules, enabling the introduction of key functional handles for further derivatization. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring sulfonamide or sulfonyl chloride functionalities.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging its reactive sites for structural diversification.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialty polymers and advanced organic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.
• Dye and Pigment Intermediate: Can be employed in the synthesis of complex dyes and organic pigments due to its aromatic core and substitutable groups.

Basic Information

Product Name	Methyl 2-Bromo-5-(Chlorosulfonyl)Benzoate
CAS No.	924867-87-8
Molecular Formula	C8H6BrClO4S
Molecular Weight	313.55 g/mol
Synonyms	Benzoic acid, 2-bromo-5-(chlorosulfonyl)-, methyl ester; Methyl 2-bromo-5-chlorosulfonylbenzoate; 2-Bromo-5-(chlorosulfonyl)benzoic acid methyl ester; 5-(Chlorosulfonyl)-2-bromobenzoic acid methyl ester; Methyl 5-chlorosulfonyl-2-bromobenzoate
EINECS	Contact for details

Quality Control

Our Methyl 2-Bromo-5-(Chlorosulfonyl)Benzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under anhydrous conditions. Keep away from incompatible materials such as strong bases, amines, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.