Description

[(1'-Acetyl-4-Oxo-3,4-Dihydrospiro[Chromene-2,4'-Piperidin]-7-Yl)Oxy]Acetic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its complex spirocyclic chromene-piperidine structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily sought after by research institutions, custom synthesis laboratories, and pharmaceutical companies engaged in the development of new chemical entities for drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders or inflammatory pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in early-stage drug discovery programs.
• Custom Synthesis & Contract Manufacturing: Employed by CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and non-commercial API batches for clinical trials.
• Chemical Biology Probes: Utilized in the development of specialized molecular probes for studying enzyme inhibition or receptor binding mechanisms.
• Academic Research: Applied in university and institutional labs for methodological development in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	[(1'-Acetyl-4-Oxo-3,4-Dihydrospiro[Chromene-2,4'-Piperidin]-7-Yl)Oxy]Acetic Acid
CAS No.	924740-45-4
Molecular Formula	C17H19NO6
Molecular Weight	333.34 g/mol
Synonyms	Acetic acid, 2-[[(1'-acetyl-4-oxo-3,4-dihydrospiro[2H-1-benzopyran-2,4'-piperidin]-7-yl)oxy]-; 7-[(Carboxymethoxy)]-1'-acetyl-3,4-dihydrospiro[2H-1-benzopyran-2,4'-piperidin]-4-one; Spiro[chromene-2,4'-piperidine]acetic acid derivative; (1'-Acetyl-4-oxospiro[chromene-2,4'-piperidine]-7-yl)oxyacetic acid; 924740-45-4; UNII-Contact for details
EINECS	Contact for details

Quality Control

Our [(1'-Acetyl-4-Oxo-3,4-Dihydrospiro[Chromene-2,4'-Piperidin]-7-Yl)Oxy]Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical R&D and process development. A comprehensive Certificate of Analysis (COA) detailing purity (HPLC), identity (IR, NMR), and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single unknown impurity	≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.