Description

2-Chloromethyl-3-Methyl-4-(3-Methoxypropoxy)Pyridine-1-Oxide is a high-purity, advanced pharmaceutical intermediate of significant commercial importance. This compound is valued for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the proton pump inhibitor (PPI) class. It is essential for manufacturers in the pharmaceutical and fine chemical industries requiring reliable, high-quality intermediates for complex synthesis pathways.

Application

• Key Intermediate for Proton Pump Inhibitors (PPIs): A critical precursor in the synthesis of modern anti-ulcer and anti-acid medications.
• Pharmaceutical Research & Development: Used in medicinal chemistry for the discovery and development of new therapeutic agents targeting gastric acid secretion.
• Fine Chemical Synthesis: Serves as a versatile building block for constructing complex heterocyclic compounds in custom synthesis projects.
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in the commercial-scale production of finished APIs under controlled GMP environments.
• Contract Manufacturing Organizations (CMOs): Supplied to CMOs specializing in the production of complex drug substances for global pharmaceutical clients.

Basic Information

Product Name	2-Chloromethyl-3-Methyl-4-(3-Methoxypropoxy)Pyridine-1-Oxide
CAS No.	924663-39-8
Molecular Formula	C12H16ClNO3
Molecular Weight	257.71 g/mol
Synonyms	2-(Chloromethyl)-3-methyl-4-(3-methoxypropoxy)pyridine 1-oxide; 4-(3-Methoxypropoxy)-3-methyl-2-pyridinylmethyl chloride N-oxide; 2-Pyridinemethanol, 2-(chloromethyl)-3-methyl-4-(3-methoxypropoxy)-, 1-oxide; PPI Intermediate; Omeprazole Related Compound; Gastric Acid Inhibitor Intermediate
EINECS	Contact for details

Quality Control

Our 2-Chloromethyl-3-Methyl-4-(3-Methoxypropoxy)Pyridine-1-Oxide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency suitable for pharmaceutical applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to ensure full traceability and compliance with customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5%
Any single impurity	≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.