Description

2-Chloro-5-Methyl-Isonicotinonitrile is a versatile and high-purity chemical intermediate of significant importance in advanced organic synthesis. Its core value lies in its functionalized pyridine core, which serves as a critical building block for constructing complex molecular architectures. This compound is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its halogenated nitrile functionality.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials due to its electron-withdrawing characteristics.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom synthesis projects and scale-up processes in fine chemical production.
• Academic and R&D Laboratories: Utilized in medicinal chemistry programs and methodological studies for constructing complex heterocyclic compounds.

Basic Information

Item	Details
Product Name	2-Chloro-5-Methyl-Isonicotinonitrile
CAS No.	924651-92-3
Molecular Formula	C7H5ClN2
Molecular Weight	152.58 g/mol
Synonyms	2-Chloro-5-methylpyridine-4-carbonitrile; 4-Cyano-2-chloro-5-methylpyridine; 5-Methyl-2-chloroisonicotinonitrile; 2-Chloro-5-methyl-4-cyanopyridine; 2-Chloro-5-picolinonitrile; Isonicotinonitrile, 2-chloro-5-methyl-; (2-Chloro-5-methyl-4-pyridyl)acetonitrile (incorrect but common alias); 924651-92-3
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-5-Methyl-Isonicotinonitrile is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.