Description

C-(2-Chloro-5-Fluoro-Pyridin-4-Yl)-Methylamine Hydrochloride is a high-purity, pharmaceutically relevant chemical intermediate with the CAS number 924651-80-9. This compound is valued for its role as a critical building block in the synthesis of advanced active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought by research and development teams, process chemists, and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A key synthon in the development of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging the pyridine core for biological activity.
• Chemical Research & Development: Serves as a versatile building block for constructing complex heterocyclic compounds in academic and industrial R&D laboratories.
• Fine Chemical Production: Employed in the custom synthesis of specialty chemicals for various high-value industrial applications.
• Ligand and Catalyst Preparation: Useful in the preparation of specialized ligands for catalytic processes in organic synthesis.

Basic Information

Item	Detail
Product Name	C-(2-Chloro-5-Fluoro-Pyridin-4-Yl)-Methylamine Hydrochloride
CAS No.	924651-80-9
Molecular Formula	C7H9Cl2FN2
Molecular Weight	211.06 g/mol
Synonyms	4-(Aminomethyl)-2-chloro-5-fluoropyridine hydrochloride; (2-Chloro-5-fluoro-4-pyridinyl)methanamine hydrochloride; 2-Chloro-5-fluoro-4-(aminomethyl)pyridine hydrochloride; 4-(Aminomethyl)-2-chloro-5-fluoropyridine HCl; 2-Chloro-5-fluoro-4-pyridinemethanamine hydrochloride; C-(2-Chloro-5-Fluoro-4-Pyridyl)Methylamine Hydrochloride
EINECS	Contact for details

Quality Control

Our C-(2-Chloro-5-Fluoro-Pyridin-4-Yl)-Methylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under dry conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.