Description

(3,5-Difluoro-Pyridin-4-Yl)-Methanol is a versatile fluorinated pyridine derivative, a crucial building block in advanced organic synthesis. Its value lies in the strategic placement of fluorine atoms and the reactive hydroxymethyl group, enabling precise molecular modifications. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex drug molecules, especially in kinase inhibitor and CNS-active compound research.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, where the difluoropyridine moiety enhances biological activity and metabolic stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and electronic materials.
• Fluorine Chemistry Studies: An important substrate for investigating new fluorination reactions and the physicochemical effects of fluorine substitution.
• Custom Synthesis & Contract Manufacturing: A high-value starting material for bespoke chemical production and scale-up services.

Basic Information

Product Name	(3,5-Difluoro-Pyridin-4-Yl)-Methanol
CAS No.	924649-16-1
Molecular Formula	C6H5F2NO
Molecular Weight	145.11 g/mol
Synonyms	4-(Hydroxymethyl)-3,5-difluoropyridine; 3,5-Difluoropyridin-4-ylmethanol; (3,5-Difluoropyridin-4-yl)methanol; 3,5-Difluoro-4-pyridinemethanol; 4-Pyridinemethanol, 3,5-difluoro-; 924649-16-1; (3,5-Difluoro-4-pyridinyl)methanol
EINECS	Contact for details

Quality Control

Our (3,5-Difluoro-Pyridin-4-Yl)-Methanol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) for every shipment, supporting your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed to exclude moisture and returned to storage immediately after use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.