Description

3,5-Dibromo-4-(1,3-dioxolan-2-yl)pyridine is a high-purity brominated pyridine derivative featuring a protected aldehyde functionality. This compound serves as a versatile and critical advanced pharmaceutical intermediate for constructing complex molecular architectures. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of new herbicides and pesticides, leveraging its halogenated pyridine core.
• Material Science Research: Serves as a precursor for functionalized ligands and monomers in advanced polymer and coordination chemistry.
• Chemical Biology Probes: Employed in the creation of tagged molecules for studying biological pathways and target engagement.
• Cross-Coupling Reactions: The bromine atoms make it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Academic & Industrial R&D: Fundamental research reagent for exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	3,5-Dibromo-4-(1,3-dioxolan-2-yl)pyridine
CAS No.	924649-13-8
Molecular Formula	C8H7Br2NO2
Molecular Weight	308.96 g/mol
Synonyms	4-(1,3-Dioxolan-2-yl)-3,5-dibromopyridine; 3,5-Dibromo-4-(1,3-dioxolan-2-yl)pyridine; 2-(3,5-Dibromopyridin-4-yl)-1,3-dioxolane; Pyridine, 3,5-dibromo-4-(1,3-dioxolan-2-yl)-; 924649-13-8
EINECS	Contact for details

Quality Control

Our 3,5-Dibromo-4-(1,3-dioxolan-2-yl)pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.