Description

1-Isopropyl-6-(2-Methylphenyl)-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate belonging to the pyrazolopyridine class of heterocyclic compounds. This compound is critical for the research and development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the synthesis of complex drug candidates.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of investigational new drugs and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Synthesis: Acts as a versatile precursor for further functionalization to create libraries of novel pyrazolopyridine derivatives.
• Biochemical Research: Employed in the development of enzyme inhibitors or receptor modulators due to its specific heterocyclic structure.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP-scale production of clinical trial materials.

Basic Information

Product Name	1-Isopropyl-6-(2-Methylphenyl)-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid
CAS No.	924243-72-1
Molecular Formula	C₁₈H₁₉N₃O₂
Molecular Weight	309.37 g/mol
Synonyms	6-(2-Methylphenyl)-1-(propan-2-yl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid; 1H-Pyrazolo[3,4-b]pyridine-4-carboxylic acid, 1-(1-methylethyl)-6-(2-methylphenyl)-; 1-Isopropyl-6-(o-tolyl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid; Pyrazolopyridine-4-carboxylic acid derivative; CAS 924243-72-1
EINECS	Contact for details

Quality Control

Our 1-Isopropyl-6-(2-Methylphenyl)-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.