Description

6-(4-Fluorophenyl)-3-Methylisoxazolo[5,4-B]Pyridine-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a distinct heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories, agrochemical innovators, and fine chemical manufacturers seeking to develop new therapeutic agents or crop protection solutions.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, or oncology.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop new chemical entities with improved efficacy and safety profiles.
• Agrochemical Development: Serves as a precursor in the research and synthesis of new-generation pesticides and herbicides, leveraging its unique fused-ring system.
• Chemical Biology Probes: Employed in the development of molecular probes for studying biological pathways and target validation in academic and industrial research settings.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of specialized, small-volume APIs for clinical trials.

Basic Information

Product Name	6-(4-Fluorophenyl)-3-Methylisoxazolo[5,4-B]Pyridine-4-Carboxylic Acid
CAS No.	923909-95-9
Molecular Formula	C15H9FN2O3
Molecular Weight	284.24 g/mol
Synonyms	6-(4-Fluorophenyl)-3-methylisoxazolo[5,4-b]pyridine-4-carboxylic acid; 3-Methyl-6-(4-fluorophenyl)isoxazolo[5,4-b]pyridine-4-carboxylic acid; 923909-95-9; Isoxazolopyridine-4-carboxylic acid derivative; 4-Carboxy-6-(4-fluorophenyl)-3-methylisoxazolo[5,4-b]pyridine; 6-(p-Fluorophenyl)-3-methylisoxazolo[5,4-b]pyridine-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 6-(4-Fluorophenyl)-3-Methylisoxazolo[5,4-B]Pyridine-4-Carboxylic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your internal specifications and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.