Description

4-(2-(Trifluoromethoxy)Phenyl)Pyridine (CAS NO 923297-56-7) is a high-value, multi-functional heterocyclic building block characterized by its unique phenylpyridine core substituted with a trifluoromethoxy group. This compound is essential for advanced research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its structure imparts desirable physicochemical properties. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to innovate new molecular entities.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the stability of the trifluoromethoxy group.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, due to its conjugated system.
• Chemical Biology Probes: Utilized as a scaffold for designing molecular probes and inhibitors for target identification and validation studies.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up services for client-specific molecules.

Basic Information

Product Name	4-(2-(Trifluoromethoxy)Phenyl)Pyridine
CAS No.	923297-56-7
Molecular Formula	C12H8F3NO
Molecular Weight	239.19 g/mol
Synonyms	2-(Trifluoromethoxy)[1,1'-biphenyl]-4-carbonitrile (incorrect but common misnomer); 4-[2-(Trifluoromethoxy)phenyl]pyridine; [2-(Trifluoromethoxy)phenyl]-4-pyridine; Pyridine, 4-[2-(trifluoromethoxy)phenyl]-; 4-(2-Trifluoromethoxyphenyl)pyridine
EINECS	Contact for details

Quality Control

Our 4-(2-(Trifluoromethoxy)Phenyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with client specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.