Description

4-[(6-Piperazin-1-Ylpyridin-3-Yl)Sulfonyl]Morpholine is a high-purity, advanced pharmaceutical intermediate featuring a unique sulfonyl-linked heterocyclic structure. This compound matters for its critical role in the synthesis of novel, biologically active molecules, particularly in medicinal chemistry research and development. Pharmaceutical companies and contract research organizations (CROs) specializing in kinase inhibitors, central nervous system (CNS) agents, and other targeted therapies need this precise building block to accelerate their drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of new chemical entities (NCEs) for therapeutic applications.
• Kinase Inhibitor Research: Used in the synthesis of potential drug candidates targeting various kinase enzymes involved in cancer and inflammatory diseases.
• CNS-Active Compound Synthesis: Serves as a building block for molecules designed to cross the blood-brain barrier for neurological and psychiatric disorder treatments.
• Medicinal Chemistry & SAR Studies: Employed in structure-activity relationship (SAR) explorations to optimize potency and selectivity of lead compounds.
• Contract Research & Development: Supplied to CROs and CDMOs for custom synthesis and scale-up projects under confidentiality agreements.
• Bioconjugation & Probe Development: Potential use in creating chemical probes for biochemical assays and diagnostic tool development due to its modifiable structure.

Basic Information

Product Name	4-[(6-Piperazin-1-Ylpyridin-3-Yl)Sulfonyl]Morpholine
CAS No.	923200-99-1
Molecular Formula	C13H20N4O3S
Molecular Weight	312.39 g/mol
Synonyms	4-[(6-Piperazin-1-ylpyridin-3-yl)sulfonyl]morpholine; 4-Morpholinesulfonamide, N-(6-(1-piperazinyl)-3-pyridinyl)-; 923200-99-1; 4-((6-(Piperazin-1-yl)pyridin-3-yl)sulfonyl)morpholine; N-(6-(Piperazin-1-yl)pyridin-3-yl)-4-morpholinesulfonamide
EINECS	Contact for details

Quality Control

Our 4-[(6-Piperazin-1-Ylpyridin-3-Yl)Sulfonyl]Morpholine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and other critical parameters is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). The product may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.