Description

1'-Cyclopentyl-6'-Oxo-1',5',6',7'-Tetrahydrospiro[Cyclopentane-1,4'-Pyrazolo[3,4-B]Pyridine]-5'-Carbonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its complex spirocyclic and fused heterocyclic structure. This compound is of significant commercial value for its role in the research and development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily sought by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in cutting-edge drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of complex drug candidates, especially kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used as a key scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery projects.
• Biochemical Tool Compound: Employed in biochemical assays to study enzyme inhibition and cellular signaling pathways.
• Custom Synthesis: A starting material for the contract manufacturing of proprietary compounds and reference standards.
• Academic Research: Utilized in university and institutional labs for the development of new synthetic methodologies involving spirocyclic systems.

Basic Information

Product Name	1'-Cyclopentyl-6'-Oxo-1',5',6',7'-Tetrahydrospiro[Cyclopentane-1,4'-Pyrazolo[3,4-B]Pyridine]-5'-Carbonitrile
CAS No.	923109-53-9
Molecular Formula	C16H18N4O
Molecular Weight	282.34 g/mol
Synonyms	1'-Cyclopentyl-6'-oxo-1',5',6',7'-tetrahydrospiro[cyclopentane-1,4'-pyrazolo[3,4-b]pyridine]-5'-carbonitrile; Spiro[cyclopentane-1,4'-pyrazolo[3,4-b]pyridine]-5'-carbonitrile, 1'-cyclopentyl-1',5',6',7'-tetrahydro-6'-oxo-; 923109-53-9; 1'-Cyclopentyl-6'-oxo-1',5',6',7'-tetrahydro-4'H-spiro[cyclopentane-1,5'-pyrazolo[3,4-b]pyridine]-5'-carbonitrile
EINECS	Contact for details

Quality Control

Our 1'-Cyclopentyl-6'-Oxo-1',5',6',7'-Tetrahydrospiro[Cyclopentane-1,4'-Pyrazolo[3,4-B]Pyridine]-5'-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.