Description

Methanone, [2-[[(2-Chloro-4-Fluorophenyl)Methoxy]Methyl]-4-Morpholinyl][6-(Trifluoromethyl)-3-Pyridinyl]- is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a key structural motif for creating novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers targeting neurological and oncological pathways.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new molecular entities.
• Process Chemistry Development: Serves as a critical starting material or intermediate in scaling up API manufacturing processes under GMP conditions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the global pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for investigating new synthetic methodologies and biological targets.

Basic Information

Product Name	Methanone, [2-[[(2-Chloro-4-Fluorophenyl)Methoxy]Methyl]-4-Morpholinyl][6-(Trifluoromethyl)-3-Pyridinyl]-
CAS No.	922409-21-0
Molecular Formula	C19H17ClF4N2O3
Molecular Weight	432.80 g/mol
Synonyms	[2-[[(2-Chloro-4-Fluorophenyl)Methoxy]Methyl]-4-Morpholinyl][6-(Trifluoromethyl)-3-Pyridinyl]methanone; (2-((2-Chloro-4-fluorobenzyloxy)methyl)morpholino)(6-(trifluoromethyl)pyridin-3-yl)methanone; 922409-21-0; UNII-9WZ8L1F8QH; 9WZ8L1F8QH
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high purity. Each lot is fully characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support development under GMP-like conditions for non-clinical and clinical phase manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 99.0%
Single Maximum Impurity	≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.