Description

Ethyl 2-(5-((tert-Butoxycarbonyl)Amino)Pyridin-2-Yl)Acetate is a high-purity, protected amino acid derivative and a key pharmaceutical intermediate. Its primary value lies in its role as a versatile building block for the synthesis of complex molecules, particularly in medicinal chemistry. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality intermediates for API synthesis and novel compound libraries.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of Active Pharmaceutical Ingredients (APIs), particularly for compounds containing a 2-aminopyridine moiety.
• Peptidomimetic Research: Used in the design and synthesis of peptide analogs and peptidomimetics due to its protected amino group and ester functionality.
• Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the development of new drug candidates targeting various diseases.
• Agrochemical Synthesis: Employed as an intermediate in the production of advanced crop protection agents and herbicides.
• Chemical Biology Probes: Utilized in the creation of labeled compounds and probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and contract research organizations (CROs/CMOs) specializing in complex organic molecules.

Basic Information

Product Name	Ethyl 2-(5-((tert-Butoxycarbonyl)Amino)Pyridin-2-Yl)Acetate
CAS No.	921940-82-1
Molecular Formula	C14H20N2O4
Molecular Weight	280.32 g/mol
Synonyms	Ethyl (5-((tert-Butoxycarbonyl)amino)pyridin-2-yl)acetate; 2-(5-((tert-Butoxycarbonyl)amino)pyridin-2-yl)acetic acid ethyl ester; Boc-6-Amino-2-pyridineacetic Acid Ethyl Ester; 5-[(tert-Butoxycarbonyl)amino]pyridine-2-acetic Acid Ethyl Ester; 2-Pyridineacetic acid, 5-[[(1,1-dimethylethoxy)carbonyl]amino]-, ethyl ester; Ethyl 2-(5-(Boc-amino)pyridin-2-yl)acetate; N-Boc-5-amino-2-pyridineacetic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 2-(5-((tert-Butoxycarbonyl)Amino)Pyridin-2-Yl)Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.