Description

Pentafluorophenyl 2-Morpholin-4-Yl-1,3-Thiazole-4-Carboxylate is a high-purity, specialized organic building block featuring a reactive pentafluorophenyl ester group. This compound is critical for researchers and manufacturers requiring efficient and selective coupling reactions, particularly in the synthesis of complex molecules. It is primarily utilized in pharmaceutical R&D, agrochemical discovery, and advanced materials science for constructing novel thiazole-containing scaffolds.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new active pharmaceutical ingredients (APIs), especially in kinase inhibitor and antimicrobial research.
• Agrochemical Synthesis: Used in the creation of novel herbicides and fungicides that incorporate the morpholinyl-thiazole pharmacophore.
• Bioconjugation & Probe Development: The activated ester moiety enables efficient labeling of biomolecules (proteins, peptides) for diagnostic and biochemical research tools.
• Polymer & Materials Chemistry: Serves as a monomer or cross-linking agent for synthesizing functional polymers with specific electronic or surface properties.
• Chemical Biology: Employed in activity-based protein profiling (ABPP) and the synthesis of covalent inhibitors for target identification studies.
• Custom Synthesis & Contract Manufacturing: An essential building block for custom synthesis services catering to the fine chemical and life science industries.

Basic Information

Product Name	Pentafluorophenyl 2-Morpholin-4-Yl-1,3-Thiazole-4-Carboxylate
CAS No.	921939-02-8
Molecular Formula	C15H9F5N2O3S
Molecular Weight	416.31 g/mol
Synonyms	4-(Morpholin-4-yl)-2-thiazolecarboxylic acid pentafluorophenyl ester; 2-Morpholino-4-thiazolecarboxylic acid pentafluorophenyl ester; Pentafluorophenyl 4-morpholinothiazole-2-carboxylate; 2-(4-Morpholinyl)-4-thiazolecarboxylic acid 2,3,4,5,6-pentafluorophenyl ester; PFP-2-Morpholin-4-yl-1,3-thiazole-4-carboxylate; PFP-Morpholinylthiazole ester; CAS 921939-02-8
EINECS	Contact for details

Quality Control

Our Pentafluorophenyl 2-Morpholin-4-Yl-1,3-Thiazole-4-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light). Keep the container tightly sealed in a dry environment to maintain stability and prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.