Description

7-(Hydroxymethyl)-4-Methyl-3,4-Dihydro-2H-Pyrido[3,2-B][1,4]Oxazine is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. It is primarily sought by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates, especially those targeting the central nervous system.
• Drug Discovery & Medicinal Chemistry: Serves as a versatile scaffold for constructing compound libraries and exploring structure-activity relationships (SAR) in early-stage R&D.
• API Synthesis: Used in the development and scale-up manufacturing processes for new chemical entities (NCEs).
• Biochemical Research: Employed as a reference standard or reagent in studies investigating enzyme inhibition or receptor binding.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects.

Basic Information

Product Name	7-(Hydroxymethyl)-4-Methyl-3,4-Dihydro-2H-Pyrido[3,2-B][1,4]Oxazine
CAS No.	921938-81-0
Molecular Formula	C9H12N2O2
Molecular Weight	180.20 g/mol
Synonyms	4-Methyl-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine-7-methanol; 7-(Hydroxymethyl)-4-methyl-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine; 4-Methyl-2H,3H,4H-pyrido[3,2-b][1,4]oxazine-7-methanol; CAS 921938-81-0; Pyridooxazine derivative intermediate; 7-Hydroxymethyl-4-methyl-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine
EINECS	Contact for details

Quality Control

Our production of 7-(Hydroxymethyl)-4-Methyl-3,4-Dihydro-2H-Pyrido[3,2-B][1,4]Oxazine adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and supporting regulatory filings for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.