Description

5-Isocyanato-1-Methylindoline is a specialized aromatic isocyanate derivative, serving as a critical building block in advanced organic synthesis. This compound is valued for its reactive isocyanate functional group, which enables the formation of ureas and carbamates, key linkages in polymer and pharmaceutical chemistry. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty polymer industries for creating novel active ingredients and high-performance materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the development of new pesticides and herbicides, where the indoline scaffold contributes to biological activity.
• Polymer Modification: Acts as a cross-linking agent or chain extender in the production of polyurethanes and other specialty polymers, enhancing material properties.
• Chemical Research: Serves as a versatile reagent in academic and industrial R&D for exploring new heterocyclic compounds and reaction pathways.
• Material Science: Employed in the surface functionalization of materials to introduce specific chemical properties or improve adhesion.

Basic Information

Product Name	5-Isocyanato-1-Methylindoline
CAS No.	921938-71-8
Molecular Formula	C10H10N2O
Molecular Weight	174.20 g/mol
Synonyms	1-Methyl-5-isocyanatoindoline; 5-Isocyanato-1-methyl-2,3-dihydro-1H-indole; 1-Methylindolin-5-yl isocyanate; 1-Methyl-2,3-dihydro-1H-indol-5-yl isocyanate
EINECS	Contact for details

Quality Control

Our 5-Isocyanato-1-Methylindoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. For customers with specific regulatory needs, we can support documentation requirements for research and cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.