Description

Pentafluorophenyl Pyrimidine-5-Carboxylate is a high-value fluorinated aromatic building block and active ester, essential for advanced synthetic chemistry. Its core value lies in enabling efficient, site-specific conjugation and derivatization reactions under mild conditions, crucial for constructing complex molecular architectures. This compound is primarily needed by researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries for developing novel active ingredients and functional polymers.

Application

• Key intermediate in the synthesis of pharmaceutical candidates, particularly kinase inhibitors and other targeted therapies.
• Building block for constructing functionalized pyrimidine cores in medicinal chemistry and drug discovery programs.
• Active ester reagent for peptide coupling and bioconjugation strategies, facilitating the attachment of pyrimidine-based motifs to biomolecules.
• Precursor for advanced materials, such as liquid crystals and organic electronic components, leveraging its fluorinated aromatic system.
• Research chemical for developing novel agrochemicals, including herbicides and fungicides with enhanced properties.
• Use in custom synthesis and contract manufacturing for producing specialized fluorinated compounds.

Basic Information

Product Name	Pentafluorophenyl Pyrimidine-5-Carboxylate
CAS No.	921938-48-9
Molecular Formula	C11H3F5N2O2
Molecular Weight	290.15 g/mol
Synonyms	Pentafluorophenyl 5-pyrimidinecarboxylate; Pyrimidine-5-carboxylic acid pentafluorophenyl ester; 5-(Pentafluorobenzoyloxy)pyrimidine; 5-Carboxypyrimidine pentafluorophenyl ester; PFP-Pyrimidine-5-COO; CAS 921938-48-9; Pentafluorophenyl 5-pyrimidylcarboxylate
EINECS	Contact for details

Quality Control

Our Pentafluorophenyl Pyrimidine-5-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your R&D and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and handled under conditions that minimize exposure to ambient light and humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.