Description

1-((2-(Trimethylsilyl)Ethoxy)Methyl)-1H-1,2,4-Triazol-3-Amine is a high-value, protected triazole derivative featuring a silyl ether moiety, which serves as a key synthetic intermediate. This compound is critical for researchers and manufacturers requiring precise chemical building blocks for complex organic synthesis. It is primarily utilized in the development of active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials where its unique functional groups enable selective transformations.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel triazole-containing drug candidates, particularly for antifungal, antiviral, and anticancer therapies.
• Agrochemical Synthesis: Used in the research and production of advanced fungicides and herbicides, leveraging the bioactive 1,2,4-triazole core.
• Organic Synthesis Reagent: Serves as a protected amine precursor in multi-step synthetic routes, where the (2-(Trimethylsilyl)ethoxy)methyl (SEM) group provides orthogonal protection strategies.
• Material Science Research: Employed in the development of specialty polymers, ligands for catalysis, and functionalized surfaces due to its reactive amine and silicon-containing side chain.
• Chemical Biology & Proteomics: Acts as a scaffold or linker molecule for the development of chemical probes and bioconjugation tools.

Basic Information

Product Name	1-((2-(Trimethylsilyl)Ethoxy)Methyl)-1H-1,2,4-Triazol-3-Amine
CAS No.	921760-98-7
Molecular Formula	C9H20N4OSi
Molecular Weight	228.37 g/mol
Synonyms	1-((2-(Trimethylsilyl)ethoxy)methyl)-1H-1,2,4-triazol-3-amine; 3-Amino-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-1,2,4-triazole; 1H-1,2,4-Triazol-3-amine, 1-((2-(trimethylsilyl)ethoxy)methyl)-; SEM-protected 3-amino-1,2,4-triazole; 921760-98-7; 1-((2-(TMS)ethoxy)methyl)-1H-1,2,4-triazol-3-amine
EINECS	Contact for details

Quality Control

Our production of 1-((2-(Trimethylsilyl)Ethoxy)Methyl)-1H-1,2,4-Triazol-3-Amine adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.