Description

1-(5-Amino-2-Pyridinyl)-3-(R)-Pyrrolidinol is a high-purity chiral building block and advanced pharmaceutical intermediate of significant commercial importance. This compound is valued for its role in the synthesis of complex, biologically active molecules, particularly in the development of new therapeutic agents. It is primarily needed by research institutions, pharmaceutical development companies, and fine chemical manufacturers engaged in asymmetric synthesis and the production of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel drug candidates, particularly for central nervous system (CNS) and anti-infective therapies.
• Asymmetric Synthesis: Utilized as a critical ligand or precursor in catalytic asymmetric reactions to induce chirality in target molecules.
• Chemical Research: Serves as a versatile building block in medicinal chemistry for constructing complex heterocyclic scaffolds.
• Process Development: Used in scaling up synthetic routes for potential Active Pharmaceutical Ingredients (APIs) under Good Manufacturing Practice (GMP) conditions.
• Reference Standard: Employed as an analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	1-(5-Amino-2-Pyridinyl)-3-(R)-Pyrrolidinol
CAS No.	921592-86-1
Molecular Formula	C9H13N3O
Molecular Weight	179.22 g/mol
Synonyms	(R)-1-(5-Amino-2-pyridinyl)-3-pyrrolidinol; 3-Pyrrolidinol, 1-(5-amino-2-pyridinyl)-, (3R)-; 1-(5-Amino-2-pyridyl)-(3R)-pyrrolidin-3-ol; (R)-1-(5-Aminopyridin-2-yl)pyrrolidin-3-ol; 921592-86-1; 1-(5-Amino-2-Pyridinyl)-3-(R)-Pyrrolidinol; (R)-1-(5-Aminopyridin-2-yl)pyrrolidin-3-ol
EINECS	Contact for details

Quality Control

Our 1-(5-Amino-2-Pyridinyl)-3-(R)-Pyrrolidinol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for prolonged exposure to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.