Description

(3R)-1-(5-Nitropyridin-2-Yl)Pyrrolidin-3-Ol CAS NO 921592-85-0 is a high-purity chiral intermediate featuring a nitropyridine and pyrrolidinol scaffold. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) and advanced agrochemicals, where stereochemical purity directly impacts efficacy and safety. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for developing novel therapeutics and crop protection agents.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of potential drug candidates, particularly in central nervous system (CNS) and anti-infective research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and insecticides, leveraging the bioactive nitropyridine moiety.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and library synthesis.
• Ligand and Catalyst Precursor: The pyrrolidinol structure can be utilized to develop chiral ligands for asymmetric catalysis.
• Reference Standard: Employed as an analytical standard for quality control and regulatory submissions in API manufacturing.

Basic Information

Product Name	(3R)-1-(5-Nitropyridin-2-Yl)Pyrrolidin-3-Ol
CAS No.	921592-85-0
Molecular Formula	C9H11N3O3
Molecular Weight	209.20 g/mol
Synonyms	(3R)-1-(5-Nitro-2-pyridinyl)-3-pyrrolidinol; (R)-1-(5-Nitropyridin-2-yl)pyrrolidin-3-ol; 921592-85-0; 3-Pyrrolidinol, 1-(5-nitro-2-pyridinyl)-, (3R)-; (R)-1-(5-Nitro-2-pyridinyl)-3-pyrrolidinol; (3R)-1-(5-Nitro-2-pyridyl)pyrrolidin-3-ol; (R)-1-(5-Nitropyridin-2-yl)pyrrolidin-3-ol
EINECS	Contact for details

Quality Control

Our (3R)-1-(5-Nitropyridin-2-Yl)Pyrrolidin-3-Ol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D and GMP-grade applications. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from direct light sources to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.