Description

1,8-Naphthyridin-2(1H)-One, 4-Amino-1-Methyl-3-Nitro- is a high-purity, specialized heterocyclic organic compound with the CAS number 921214-37-1. This chemical serves as a critical advanced intermediate in the synthesis of complex active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for developing novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel drug candidates, particularly in therapeutic areas requiring complex nitrogen-containing heterocycles.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its unique naphthyridine core structure.
• Organic Light-Emitting Diode (OLED) Materials: Acts as a precursor for electron-transport or host materials in OLED displays and lighting due to its electron-deficient aromatic system.
• Coordination Chemistry & Ligand Synthesis: Serves as a starting material for creating chelating ligands used in catalysis and metal-organic frameworks (MOFs).
• Dye & Pigment Intermediate: Utilized in the production of specialized dyes and pigments where the amino and nitro functional groups allow for further chemical modifications.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and the exploration of new chemical reactions involving functionalized naphthyridines.

Basic Information

Product Name	1,8-Naphthyridin-2(1H)-One, 4-Amino-1-Methyl-3-Nitro-
CAS No.	921214-37-1
Molecular Formula	C9H8N4O3
Molecular Weight	220.19 g/mol
Synonyms	4-Amino-1-methyl-3-nitro-1,8-naphthyridin-2(1H)-one; 4-Amino-1-methyl-3-nitro-1,8-naphthyridin-2-ol; 1-Methyl-4-amino-3-nitro-1,8-naphthyridin-2-one; 3-Nitro-4-amino-1-methyl-1,8-naphthyridin-2(1H)-one; 4-Amino-1-methyl-3-nitro-2(1H)-1,8-naphthyridinone; 921214-37-1; 4-Amino-1-methyl-3-nitro-1H-1,8-naphthyridin-2-one
EINECS	Contact for details

Quality Control

Our 1,8-Naphthyridin-2(1H)-One, 4-Amino-1-Methyl-3-Nitro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with data from advanced techniques like HPLC, NMR, and mass spectrometry. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical research and production applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Yellow to brown powder or crystals
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.