Description

1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylic Acid, 5-(Trifluoromethyl)-, Ethyl Ester is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its core value lies in the unique pyrrolopyridine scaffold combined with a strategically placed trifluoromethyl group, offering significant potential for modulating the physicochemical and biological properties of target molecules. This compound is critically needed by research and development chemists in the pharmaceutical and agrochemical industries for the discovery and development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other small molecule therapeutics targeting various disease pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the trifluoromethyl group can enhance metabolic stability and bioavailability.
• Material Science: Serves as a specialized monomer or building block for creating advanced organic electronic materials, such as OLEDs or conductive polymers.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.
• Academic & Institutional Research: Used in university and government laboratories for fundamental research in heterocyclic chemistry and medicinal chemistry.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylic Acid, 5-(Trifluoromethyl)-, Ethyl Ester
CAS No.	920978-97-8
Molecular Formula	C11H9F3N2O2
Molecular Weight	258.20 g/mol
Synonyms	Ethyl 5-(Trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxylate; 5-Trifluoromethyl-1H-pyrrolo[2,3-b]pyridine-2-carboxylic Acid Ethyl Ester; 1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid, 5-(trifluoromethyl)-, ethyl ester; 920978-97-8; Ethyl 5-(trifluoromethyl)-7-azaindole-2-carboxylate; 5-(Trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide material with a typical purity of ≥97% (by HPLC), suitable for research and development applications. For advanced pharmaceutical projects, higher purity grades (≥98% or ≥99%) can be supplied upon request. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every batch. Our quality system is designed to support cGMP compliance for drug substance intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to prevent degradation. Keep away from incompatible materials such as strong bases and fluorides.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.