Description

1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylic Acid, 1-(Phenylmethyl)-, Ethyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its fused pyrrolopyridine core. This compound is of significant value for its role as a key building block in the synthesis of complex bioactive molecules, particularly in medicinal chemistry. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, including kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of targeted drug candidates, especially those with kinase inhibitory activity.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Active Pharmaceutical Ingredient (API) Development: Used in the research and process development stages for creating new active pharmaceutical ingredients.
• Biochemical Tool Compound: May be utilized in biochemical assays to study enzyme function and cellular signaling pathways.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up services for the life sciences industry.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylic Acid, 1-(Phenylmethyl)-, Ethyl Ester
CAS No.	920978-91-2
Molecular Formula	C17H16N2O2
Molecular Weight	280.32 g/mol
Synonyms	1-Benzyl-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid ethyl ester; Ethyl 1-benzyl-1H-pyrrolo[2,3-b]pyridine-2-carboxylate; 1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid, 1-(phenylmethyl)-, ethyl ester; 1-Benzyl-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid ethyl ester; 920978-91-2; 1-Benzyl-ethyl 1H-pyrrolo[2,3-b]pyridine-2-carboxylate
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support development and commercial projects requiring material that meets GMP-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.