Description

1H-Pyrrolo[2,3-B]Pyridine-3-Carbonitrile, 4-Chloro-1-(Phenylsulfonyl)- is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of targeted therapeutics.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, especially kinase inhibitors and other targeted small molecules.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Organic Synthesis: Serves as a versatile precursor for further functionalization, enabling the creation of diverse chemical libraries for screening.
• Biochemical Tool Compound: Potential use in the development of biochemical probes for studying specific biological pathways and targets.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine-3-Carbonitrile, 4-Chloro-1-(Phenylsulfonyl)-
CAS No.	920965-86-2
Molecular Formula	C14H8ClN3O2S
Molecular Weight	317.75 g/mol
Synonyms	4-Chloro-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile; 4-Chloro-1-(benzenesulfonyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile; 1-(Phenylsulfonyl)-4-chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile; 920965-86-2; 4-Chloro-1-tosyl-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile (common alias); 1H-Pyrrolo[2,3-b]pyridine-3-carbonitrile, 4-chloro-1-(phenylsulfonyl)-
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine-3-Carbonitrile, 4-Chloro-1-(Phenylsulfonyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.