Description

tert-Butyl n-[2-[2-(6-Chlorohexyloxy)Ethoxy]Ethyl]Carbamate is a specialized, high-purity organic intermediate featuring a protected amine group and a terminal chloroalkyl chain. This compound matters for its role as a critical building block in the synthesis of complex molecules, enabling the precise introduction of functionalized polyethylene glycol (PEG) linkers. It is primarily needed by research and development chemists in the pharmaceutical and bioconjugation sectors for creating targeted drug delivery systems, antibody-drug conjugates (ADCs), and advanced polymer materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and prodrugs requiring PEGylated linkers.
• Antibody-Drug Conjugate (ADC) Development: Used to construct the linker-payload complex, connecting cytotoxic agents to monoclonal antibodies.
• Bioconjugation Chemistry: Facilitates the attachment of drugs, dyes, or other molecules to proteins, peptides, or nanoparticles.
• Polymer & Material Science: Serves as a monomer or functionalization agent for creating specialized polymers with tailored properties.
• Prodrug Synthesis: Employed in designing prodrugs where controlled release of the active moiety is required.
• Research & Development: A valuable tool in medicinal chemistry for structure-activity relationship (SAR) studies and novel compound library generation.

Basic Information

Product Name	tert-Butyl n-[2-[2-(6-Chlorohexyloxy)Ethoxy]Ethyl]Carbamate
CAS No.	920264-35-3
Molecular Formula	C15H30ClNO4
Molecular Weight	323.86 g/mol
Synonyms	Boc-NH-PEG2-C6-Cl; 1-(6-Chlorohexyloxy)-2-[2-[(tert-butoxycarbonyl)amino]ethoxy]ethane; tert-Butyl (2-{2-[(6-chlorohexyl)oxy]ethoxy}ethyl)carbamate; 2-{2-[(6-Chlorohexyl)oxy]ethoxy}ethylcarbamic acid tert-butyl ester; N-Boc-2,2'-(ethylenedioxy)diethylamine 6-chlorohexyl ether; N-(tert-Butoxycarbonyl)-2,2'-(ethylenedioxy)bis(ethylamine) 6-chlorohexyl ether; PEG2-C6-Cl Boc-amine
EINECS	Contact for details

Quality Control

Our tert-Butyl n-[2-[2-(6-Chlorohexyloxy)Ethoxy]Ethyl]Carbamate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive (store away from light). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Typical: 97-99%)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.