Description

1H-Pyrazolo[3,4-B]Pyridine-1-Carboxylicacid,3-Iodo-,1,1-Dimethylethylester is a high-purity, advanced pharmaceutical intermediate with a CAS number of 920036-34-6. This compound is a critical building block in modern medicinal chemistry, valued for its unique pyrazolopyridine scaffold and reactive iodo substituent. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug candidates, particularly those targeting kinase inhibition.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies due to its versatile functional groups.
• Organic Synthesis Building Block: The iodo group enables further functionalization via cross-coupling reactions (e.g., Suzuki, Sonogashira) for creating diverse chemical libraries.
• Agrochemical Research: Potential application in the development of new crop protection agents and herbicides.
• Material Science Exploration: Investigated as a component in the synthesis of organic electronic materials and ligands for catalysis.

Basic Information

Product Name	1H-Pyrazolo[3,4-B]Pyridine-1-Carboxylicacid,3-Iodo-,1,1-Dimethylethylester
CAS No.	920036-34-6
Molecular Formula	C12H12IN3O2
Molecular Weight	357.15 g/mol
Synonyms	3-Iodo-1H-pyrazolo[3,4-b]pyridine-1-carboxylic acid tert-butyl ester; tert-Butyl 3-iodo-1H-pyrazolo[3,4-b]pyridine-1-carboxylate; 1-(tert-Butoxycarbonyl)-3-iodo-1H-pyrazolo[3,4-b]pyridine; 920036-34-6; 3-Iodo-1-Boc-1H-pyrazolo[3,4-b]pyridine; 1-Boc-3-iodo-1H-pyrazolo[3,4-b]pyridine; tert-Butyl 3-iodopyrazolo[3,4-b]pyridine-1-carboxylate
EINECS	Contact for details

Quality Control

Our production of 1H-Pyrazolo[3,4-B]Pyridine-1-Carboxylicacid,3-Iodo-,1,1-Dimethylethylester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques like HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.