Description

1H-Pyrazolo[3,4-B]Pyridine-1-Carboxylic Acid, 6-Fluoro-3-Methyl-, 1,1-Dimethylethyl Ester is a high-purity, fluorinated pyrazolopyridine derivative serving as a critical pharmaceutical intermediate and building block in advanced organic synthesis. Its value lies in its precise molecular architecture, which is essential for constructing complex bioactive molecules, particularly in medicinal chemistry. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel drug candidates, particularly kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis Building Block: Employed in complex multi-step syntheses to introduce the fluorinated pyrazolopyridine moiety into larger molecular frameworks.
• Agrochemical Research: Potential application as an intermediate in the synthesis of advanced crop protection agents and herbicides.
• Material Science: Investigated for use in the development of specialty chemicals and advanced organic materials.

Basic Information

Product Name	1H-Pyrazolo[3,4-B]Pyridine-1-Carboxylic Acid, 6-Fluoro-3-Methyl-, 1,1-Dimethylethyl Ester
CAS No.	920036-29-9
Molecular Formula	C13H14FN3O2
Molecular Weight	263.27 g/mol
Synonyms	tert-Butyl 6-fluoro-3-methyl-1H-pyrazolo[3,4-b]pyridine-1-carboxylate; 6-Fluoro-3-methyl-1H-pyrazolo[3,4-b]pyridine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-6-fluoro-3-methyl-1H-pyrazolo[3,4-b]pyridine; 920036-29-9; tert-Butyl 6-fluoro-3-methylpyrazolo[3,4-b]pyridine-1-carboxylate; 1-Boc-6-fluoro-3-methyl-1H-pyrazolo[3,4-b]pyridine
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to verify identity, purity, and consistency. Certificates of Analysis (COA) are available upon request, detailing batch-specific results. Our commitment to quality supports applications requiring high-purity intermediates for GMP and research use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.