Description

5-Bromo-1'-Methylspiro[Indoline-3,4'-Piperidin]-2-One is a high-purity, advanced pharmaceutical intermediate characterized by its unique spirocyclic structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of complex bioactive molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within central nervous system (CNS) and oncology research pipelines.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of novel drug candidates, especially those targeting specific receptor subtypes.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies and lead optimization programs to develop new chemical entities.
• CNS Drug Development: A valuable scaffold for creating compounds with potential activity in neurological and psychiatric disorders.
• Oncological Research: Employed in the design and synthesis of potential kinase inhibitors and other targeted cancer therapies.
• Chemical Biology: Utilized as a molecular probe to study biological pathways and protein-ligand interactions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Product Name	5-Bromo-1'-Methylspiro[Indoline-3,4'-Piperidin]-2-One
CAS No.	920023-50-3
Molecular Formula	C14H17BrN2O
Molecular Weight	309.20 g/mol
Synonyms	5-Bromo-1'-methylspiro[indoline-3,4'-piperidin]-2-one; 5-Bromo-1'-methyl-2-oxospiro[indoline-3,4'-piperidine]; Spiro[indoline-3,4'-piperidin]-2-one, 5-bromo-1'-methyl-; 920023-50-3; 5-Bromo-1'-methylspiro[indole-3,4'-piperidine]-2-one; 1'-Methyl-5-bromospiro[indoline-3,4'-piperidin]-2-one
EINECS	Contact for details

Quality Control

Our 5-Bromo-1'-Methylspiro[Indoline-3,4'-Piperidin]-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (NMR, IR, MS), to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.