Description

5-Bromospiro[Isobenzofuran-1(3H) is a high-value brominated spirocyclic compound, a versatile and critical building block in advanced organic synthesis. Its unique fused-ring structure makes it an essential intermediate for constructing complex molecular architectures with specific steric and electronic properties. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, leveraging the bromine atom for further functionalization.
• Material Science Research: Serves as a precursor for organic light-emitting diodes (OLEDs), liquid crystals, and other advanced organic electronic materials.
• Academic & R&D: Employed in methodological studies and as a model compound for exploring new spirocyclization and cross-coupling reactions.
• Ligand & Catalyst Development: The spiro framework can be utilized to develop novel chiral ligands or organocatalysts for asymmetric synthesis.

Basic Information

Product Name	5-Bromospiro[Isobenzofuran-1(3H)
CAS No.	920023-36-5
Molecular Formula	C8H5BrO
Molecular Weight	197.03 g/mol
Synonyms	5-Bromospiro[2-benzofuran-1(3H),1'-cyclopropane]; 5-Bromo-1-oxaspiro[2.5]octa-5,7-dien-4-one; 5-Bromo-1-oxaspiro[2.5]octa-5,7-diene-4-one; 5-Bromospiro[isobenzofuran-1(3H),1'-cyclopropane]; 5-Bromospiro(isobenzofuran-1(3H),1'-cyclopropane); 5-Bromo-1-oxaspiro[2.5]octa-5,7-dien-4-one; 5-Bromo-1-oxaspiro[2.5]octa-5,7-diene-4-one
EINECS	Contact for details

Quality Control

Our 5-Bromospiro[Isobenzofuran-1(3H) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.