Description

Ethyl 4-({[5-(1,1-Dioxido-1,2-Thiazinan-2-Yl)-2-Methoxyphenyl]Sulfonyl}Amino)-1-Piperidinecarboxylate is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound matters for its role as a critical building block in modern medicinal chemistry, enabling the development of targeted therapeutics. It is primarily needed by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the discovery and production of novel drug candidates, particularly in areas requiring sophisticated sulfonamide and piperidine motifs.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new chemical entities (NCEs) and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a core scaffold or building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Sulfonamide-Based Drug Synthesis: Specifically valuable for constructing molecules containing the sulfonamide functional group, common in enzyme inhibitors.
• Piperidine Derivative Production: Serves as a precursor for creating diverse piperidine-containing compounds with potential biological activity.
• Contract Manufacturing: Supplied to CDMOs for scale-up synthesis under current Good Manufacturing Practice (cGMP) conditions for clinical trial material production.
• Biochemical Research: May be utilized as a tool compound or probe in biochemical assays to study specific biological pathways.

Basic Information

Product Name	Ethyl 4-({[5-(1,1-Dioxido-1,2-Thiazinan-2-Yl)-2-Methoxyphenyl]Sulfonyl}Amino)-1-Piperidinecarboxylate
CAS No.	919972-24-0
Molecular Formula	C19H29N3O6S2
Molecular Weight	459.58 g/mol
Synonyms	Ethyl 4-[[[5-(1,1-Dioxo-1,2-thiazinan-2-yl)-2-methoxyphenyl]sulfonyl]amino]piperidine-1-carboxylate; 1-Piperidinecarboxylic acid, 4-[[[5-(1,1-dioxido-1,2-thiazinan-2-yl)-2-methoxyphenyl]sulfonyl]amino]-, ethyl ester; 4-({[5-(1,1-Dioxido-1,2-thiazinan-2-yl)-2-methoxyphenyl]sulfonyl}amino)-1-piperidinecarboxylic acid ethyl ester; Ethyl 4-({[5-(1,1-dioxo-1λ⁶,2-thiazinan-2-yl)-2-methoxyphenyl]sulfonyl}amino)piperidine-1-carboxylate; CAS 919972-24-0
EINECS	Contact for details

Quality Control

Our Ethyl 4-({[5-(1,1-Dioxido-1,2-Thiazinan-2-Yl)-2-Methoxyphenyl]Sulfonyl}Amino)-1-Piperidinecarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D and cGMP manufacturing. Certificates of Analysis (COA) detailing specifications and test results are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.