Description

[2-[(Tetrahydropyran-4-Yl)Amino]Ethyl]Carbamic Acid tert-Butyl Ester CAS NO 919835-79-3 is a high-purity, protected amine derivative featuring a tetrahydropyranyl (THP) moiety, serving as a critical building block in advanced organic synthesis. Its primary value lies in its role as a versatile synthetic intermediate, enabling the construction of complex molecules with precise stereochemistry and functional group compatibility. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, particularly those requiring chiral amine scaffolds.
• Agrochemical Research: Used in the development of novel pesticides and herbicides where the tetrahydropyranyl group contributes to bioavailability and stability.
• Peptide Mimetics & PROTACs: Serves as a crucial component in the design of peptide-like molecules and Proteolysis Targeting Chimeras (PROTACs) for targeted protein degradation.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands and organocatalysts for asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.
• Academic & R&D Laboratories: Used in medicinal chemistry and process chemistry research for method development and exploring new chemical spaces.

Basic Information

Item	Details
Product Name	[2-[(Tetrahydropyran-4-Yl)Amino]Ethyl]Carbamic Acid tert-Butyl Ester
CAS No.	919835-79-3
Molecular Formula	C12H24N2O3
Molecular Weight	244.33 g/mol
Synonyms	N-(2-((Tetrahydro-2H-pyran-4-yl)amino)ethyl)carbamic acid tert-butyl ester; tert-Butyl N-[2-[(oxan-4-yl)amino]ethyl]carbamate; 2-[(Tetrahydro-2H-pyran-4-yl)amino]ethylcarbamic Acid 1,1-Dimethylethyl Ester; Boc-NH-(CH2)2-NH-THP; (2-((Tetrahydro-2H-pyran-4-yl)amino)ethyl)carbamic acid tert-butyl ester; N-Boc-2-(tetrahydro-2H-pyran-4-ylamino)ethylamine; tert-Butyl (2-((tetrahydro-2H-pyran-4-yl)amino)ethyl)carbamate
EINECS	Contact for details

Quality Control

Our [2-[(Tetrahydropyran-4-Yl)Amino]Ethyl]Carbamic Acid tert-Butyl Ester is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment. We support development and commercial projects requiring compliance with cGMP and ICH Q7 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.