Description

n-(3-{[(2-Chloropyridin-3-Yl)Carbonyl]Amino}Propyl)Pyrazine-2-Carboxamide is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a versatile building block for creating novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new drug candidates, particularly in areas requiring sophisticated heterocyclic chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities.
• API Synthesis: Serves as a critical precursor in the multi-step manufacturing process of complex active pharmaceutical ingredients.
• Biochemical Research: Employed as a tool compound in biochemical assays to study enzyme inhibition and cellular pathways.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for exploratory research in organic and heterocyclic chemistry.

Basic Information

Product Name	n-(3-{[(2-Chloropyridin-3-Yl)Carbonyl]Amino}Propyl)Pyrazine-2-Carboxamide
CAS No.	919719-72-5
Molecular Formula	C14H13ClN6O2
Molecular Weight	332.75 g/mol
Synonyms	N-[3-[[(2-Chloro-3-pyridinyl)carbonyl]amino]propyl]-2-pyrazinecarboxamide; 919719-72-5; 2-Pyrazinecarboxamide, N-[3-[[(2-chloro-3-pyridinyl)carbonyl]amino]propyl]-; UNII-4Q6W2V7J0Z; 4Q6W2V7J0Z; BDBM50389319; AKOS025310923; ZINC000103014511; SCHEMBL23346811
EINECS	Contact for details

Quality Control

Our n-(3-{[(2-Chloropyridin-3-Yl)Carbonyl]Amino}Propyl)Pyrazine-2-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS). We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment ensures material suitable for demanding applications in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.