Description

(3R)-5-Oxo-3-Pyrrolidinecarboxylic Acid Ethyl Ester is a high-purity chiral intermediate of significant importance in modern synthetic chemistry. This compound is valued for its role as a key building block in the synthesis of complex, biologically active molecules, particularly in the pharmaceutical sector. It is primarily needed by research institutions and manufacturers developing active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals where stereochemical control is critical.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the research and production of various APIs, including potential treatments for neurological disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of advanced, enantiomerically pure pesticides and herbicides.
• Asymmetric Catalysis Research: Serves as a valuable substrate or ligand precursor in the development of new catalytic systems.
• Peptidomimetic Chemistry: Acts as a constrained proline analog for constructing novel peptide-like structures in drug discovery.
• Fine Chemical Production: Employed in the synthesis of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic & R&D: Utilized in university and corporate laboratories for methodological studies and the synthesis of novel chemical entities.

Basic Information

Product Name	(3R)-5-Oxo-3-Pyrrolidinecarboxylic Acid Ethyl Ester
CAS No.	919513-66-9
Molecular Formula	C7H11NO3
Molecular Weight	157.17 g/mol
Synonyms	(R)-5-Oxo-3-pyrrolidinecarboxylic acid ethyl ester; Ethyl (3R)-5-oxopyrrolidine-3-carboxylate; (R)-Ethyl 5-oxopyrrolidine-3-carboxylate; (3R)-5-Oxopyrrolidine-3-carboxylic Acid Ethyl Ester; (R)-NSC 339539; (R)-Ethyl 2-oxopyrrolidine-4-carboxylate (related tautomer); (R)-4-Carbethoxy-2-pyrrolidinone
EINECS	Contact for details

Quality Control

Our (3R)-5-Oxo-3-Pyrrolidinecarboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed specifications for identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is stable under these conditions but should be kept away from strong bases and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.