Description

3-Pyridinecarboxylic Acid, 2,6-Dichloro-5-Cyano-, Ethyl Ester is a high-value, multi-functional heterocyclic building block designed for advanced chemical synthesis. This compound matters for its role as a critical intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its unique substitution pattern enables precise molecular construction. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce complex pyridine-based scaffolds into their target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides with specific modes of action.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands used in catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functional organic materials and dyes due to its electron-deficient pyridine core.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring dichloro-cyano pyridine derivatives.
• Academic & Industrial R&D: Utilized in exploratory chemistry to build molecular libraries for high-throughput screening.

Basic Information

Product Name	3-Pyridinecarboxylic Acid, 2,6-Dichloro-5-Cyano-, Ethyl Ester
CAS No.	919354-52-2
Molecular Formula	C9H6Cl2N2O2
Molecular Weight	245.06 g/mol
Synonyms	Ethyl 2,6-Dichloro-5-cyanonicotinate; 2,6-Dichloro-5-cyano-3-pyridinecarboxylic Acid Ethyl Ester; 2,6-Dichloro-5-cyanopyridine-3-carboxylic Acid Ethyl Ester; 5-Cyano-2,6-dichloronicotinic Acid Ethyl Ester; Nicotinic acid, 2,6-dichloro-5-cyano-, ethyl ester; Ethyl 2,6-dichloro-5-cyanopyridine-3-carboxylate
EINECS	Contact for details

Quality Control

Our 3-Pyridinecarboxylic Acid, 2,6-Dichloro-5-Cyano-, Ethyl Ester is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize moisture exposure. Store away from incompatible materials such as strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.