Description

1-(3-Cyano-5-(Ethoxycarbonyl)-6-Methylpyridin-2-Yl)Piperidine-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of new drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug molecules, especially those targeting central nervous system (CNS) disorders or metabolic diseases.
• Research & Development (R&D): Used in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new bioactive compounds.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a core structural unit in the manufacturing process of proprietary APIs under GMP conditions.
• Chemical Biology Probes: Utilized in the development of specialized probes for studying enzyme function or receptor interactions in biological systems.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	1-(3-Cyano-5-(Ethoxycarbonyl)-6-Methylpyridin-2-Yl)Piperidine-4-Carboxylic Acid
CAS No.	919354-24-8
Molecular Formula	C17H21N3O4
Molecular Weight	331.37 g/mol
Synonyms	4-Piperidinecarboxylic acid, 1-[3-cyano-5-(ethoxycarbonyl)-6-methyl-2-pyridinyl]-; 1-(3-Cyano-5-(ethoxycarbonyl)-6-methylpyridin-2-yl)piperidine-4-carboxylic acid; 2-(4-Carboxypiperidin-1-yl)-5-ethoxycarbonyl-6-methylnicotinonitrile; 919354-24-8; Nicotinonitrile, 2-(4-carboxy-1-piperidinyl)-5-(ethoxycarbonyl)-6-methyl-
EINECS	Contact for details

Quality Control

Our production of 1-(3-Cyano-5-(Ethoxycarbonyl)-6-Methylpyridin-2-Yl)Piperidine-4-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and tested against rigorous in-house specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.