Description

2-Thiophenecarboxylic Acid, 5-Chloro-3-Fluoro-, Methyl Ester is a high-purity, multi-functional heterocyclic building block designed for advanced chemical synthesis. This compound is valued for its precise molecular architecture, which introduces both halogen and ester functionalities onto a thiophene core, enabling targeted modifications in complex molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients, as well as by material scientists exploring advanced organic electronic materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for introducing halogenated thiophene motifs.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides where the thiophene scaffold contributes to biological activity.
• Material Science Research: Serves as a precursor for functionalized monomers in the development of conductive polymers and organic semiconductors.
• Chemical Research: Employed in organic synthesis as a versatile building block for cross-coupling reactions and further functional group transformations.
• Ligand and Catalyst Development: Utilized to create specialized ligands for metal complexes used in catalytic processes.

Basic Information

Product Name	2-Thiophenecarboxylic Acid, 5-Chloro-3-Fluoro-, Methyl Ester
CAS No.	919122-19-3
Molecular Formula	C7H4ClFO2S
Molecular Weight	206.62 g/mol
Synonyms	Methyl 5-Chloro-3-fluorothiophene-2-carboxylate; 5-Chloro-3-fluoro-2-thiophenecarboxylic Acid Methyl Ester; 5-Chloro-3-fluorothiophene-2-carboxylic acid methyl ester; Methyl 5-chloro-3-fluorothiophene-2-carboxylate; 2-Thiophenecarboxylic acid, 5-chloro-3-fluoro-, methyl ester
EINECS	Contact for details

Quality Control

Our 2-Thiophenecarboxylic Acid, 5-Chloro-3-Fluoro-, Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and batch-to-batch consistency for critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider using inert atmosphere packaging to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.