Description

1H-Indole-2-Carboxylic Acid, 7-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-, Ethyl Ester is a high-value, multi-functional boronic ester derivative of indole-2-carboxylate, serving as a critical synthetic intermediate. Its core value lies in enabling efficient, site-specific cross-coupling reactions, particularly Suzuki-Miyaura couplings, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in pharmaceutical development, agrochemical synthesis, and advanced materials science who require precise functionalization of the indole scaffold.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science Precursor: Employed in the creation of organic electronic materials, such as OLED emitters and charge-transport layers.
• Chemical Biology Probes: Facilitates the synthesis of labeled compounds and molecular probes for studying biological pathways and protein interactions.
• Academic & R&D: A versatile reagent for methodological development in organic synthesis and catalysis research within university and industrial laboratories.
• Ligand Synthesis: Serves as a precursor for creating sophisticated ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	1H-Indole-2-Carboxylic Acid, 7-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-, Ethyl Ester
CAS No.	919119-62-3
Molecular Formula	C₁₇H₂₂BNO₄
Molecular Weight	315.18 g/mol
Synonyms	Ethyl 7-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-2-carboxylate; 7-BPin-1H-indole-2-carboxylic acid ethyl ester; 1H-Indole-2-carboxylic acid, 7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, ethyl ester; Ethyl 7-BPin-indole-2-carboxylate; 7-(Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-2-carboxylic acid ethyl ester; BPin-Indole-2-COOEt; CAS 919119-62-3
EINECS	Contact for details

Quality Control

Every batch of our 1H-Indole-2-Carboxylic Acid, 7-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-, Ethyl Ester is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure high purity, identity, and batch-to-batch consistency. Our standard quality commitment includes comprehensive analysis via HPLC, NMR, and MS. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.