Description

5-Methoxy-2-Methyl-7-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Indole is a high-value, multi-functional indole derivative containing a pinacol boronate ester group, making it a critical building block for modern synthetic chemistry. This compound matters because it enables efficient cross-coupling reactions, such as the Suzuki-Miyaura reaction, which is fundamental for constructing complex molecules in a controlled and scalable manner. Pharmaceutical R&D and fine chemical synthesis laboratories need this advanced intermediate for developing novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used to create advanced active ingredients for crop protection products through efficient cross-coupling methodologies.
• Material Science Research: Serves as a building block for organic electronic materials, including OLEDs and semiconductors, due to the indole-boronate structure.
• Chemical Biology Probes: Employed in the development of labeled compounds and molecular probes for diagnostic and research applications.
• Catalyst & Ligand Development: Acts as a starting material for synthesizing novel ligands and catalysts used in asymmetric synthesis.
• Academic & Contract Research: Essential for methodological development and complex molecule construction in academic and CRO laboratory settings.

Basic Information

Product Name	5-Methoxy-2-Methyl-7-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Indole
CAS No.	919119-61-2
Molecular Formula	C₁₆H₂₂BNO₃
Molecular Weight	287.16 g/mol
Synonyms	7-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-5-methoxy-2-methyl-1H-indole; 5-Methoxy-2-methyl-1H-indole-7-boronic acid pinacol ester; 5-Methoxy-2-methylindole-7-boronic acid pinacol ester; 919119-61-2; 7-Borono-5-methoxy-2-methylindole pinacol ester; 5-Methoxy-2-methyl-7-(pinacolatoboryl)-1H-indole; 7-(Pinacolatoboryl)-5-methoxy-2-methylindole
EINECS	Contact for details

Quality Control

Our 5-Methoxy-2-Methyl-7-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Indole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and structural integrity suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light). Keep the container tightly sealed under an inert atmosphere to prevent degradation and moisture uptake. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.