Description

2-Propenamide, N,n-Diethyl-3-(9-Methyl-7,8,12-Trioxaspiro[5.6]Dodec-9-Yl)-, (2E)- is a specialized acrylamide derivative featuring a unique spirocyclic trioxane moiety. This compound matters as a high-value chemical intermediate, offering a reactive acrylamide group and a complex, functionalized backbone for advanced synthesis. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates with complex spirocyclic or polyether motifs.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides where its specific structure can contribute to unique modes of action.
• Polymer Science: Acts as a functional monomer or cross-linking agent for creating specialty polymers with tailored properties, such as responsive hydrogels or high-performance coatings.
• Material Chemistry: Employed in the research of advanced materials, including dendrimers, molecular cages, or components for organic electronics.
• Chemical Biology: Utilized as a probe or linker molecule in bioconjugation and proteomics research due to its reactive acrylamide group.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic synthesis, particularly in reactions involving Michael additions or radical polymerizations initiated from complex substrates.

Basic Information

Product Name	2-Propenamide, N,n-Diethyl-3-(9-Methyl-7,8,12-Trioxaspiro[5.6]Dodec-9-Yl)-, (2E)-
CAS No.	918901-97-0
Molecular Formula	C19H31NO4
Molecular Weight	337.46 g/mol
Synonyms	(2E)-N,N-Diethyl-3-(9-methyl-7,8,12-trioxaspiro[5.6]dodec-9-yl)prop-2-enamide; N,N-Diethyl-3-(9-methyl-7,8,12-trioxaspiro[5.6]dodec-9-yl)-(2E)-2-propenamide; 9-Methyl-9-[(1E)-3-(diethylamino)-3-oxo-1-propen-1-yl]-7,8,12-trioxaspiro[5.6]dodecane; Acrylamide, N,N-diethyl-3-(9-methyl-7,8,12-trioxaspiro[5.6]dodec-9-yl)-, (E)-; Spirocyclic Acrylamide Derivative
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced and analyzed under strict quality protocols to ensure consistency and purity for critical research and development applications. We provide comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles, supported by analytical techniques including HPLC, NMR, and MS. Our quality system is designed to meet the stringent requirements of cGMP and ISO 9001 standards for laboratory and pilot-scale materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive and should be handled under an inert atmosphere when appropriate to prevent degradation. Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Individual impurity ≤ 2.0%
Total Impurities	≤ 5.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.