Description

tert-Butyl 4-(2,6-Difluorobenzylamino)Piperidine-1-Carboxylate is a high-purity, protected piperidine derivative that serves as a critical building block in modern organic synthesis. This compound is valued for its role as a versatile intermediate in the development of active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in medicinal chemistry programs.
• API Synthesis: Used in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs), leveraging its protected amine functionality.
• Agrochemical Research: Serves as a building block for creating new molecules with potential herbicidal or pesticidal activity.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands and organocatalysts for asymmetric synthesis.
• Chemical Biology Probes: Useful for synthesizing labeled compounds or probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up production under cGMP conditions.

Basic Information

Product Name	tert-Butyl 4-(2,6-Difluorobenzylamino)Piperidine-1-Carboxylate
CAS No.	918537-17-4
Molecular Formula	C17H24F2N2O2
Molecular Weight	326.38 g/mol
Synonyms	1-Boc-4-[(2,6-difluorobenzyl)amino]piperidine; 4-[(2,6-Difluorobenzyl)amino]-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; tert-Butyl 4-[(2,6-difluorophenyl)methyl]amino-1-piperidinecarboxylate; N-(2,6-Difluorobenzyl)-4-amino-1-Boc-piperidine; 1-Boc-4-(2,6-difluorobenzylamino)piperidine; 918537-17-4; BOC-4-(2,6-Difluorobenzylamino)piperidine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(2,6-Difluorobenzylamino)Piperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specification results. Our quality commitment supports applications requiring high standards, including pharmaceutical R&D under ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.