Description

1H-Pyrrolo[2,3-B]Pyridine, 4-Chloro-3-Nitro- is a high-purity, heterocyclic organic building block of significant interest in advanced chemical synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. Industries requiring precise and reliable fine chemical intermediates for research and production, such as medicinal chemistry and material science, are the primary users of this material.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its fused pyrrolopyridine core.
• Material Science: Acts as a building block for organic electronic materials, including organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Synthesis: Employed in academic and industrial R&D for constructing complex heterocyclic frameworks and exploring new reaction pathways.
• Bioconjugation & Probe Development: Useful for creating fluorescent probes or biochemical tools due to its modifiable nitro and chloro functional groups.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine, 4-Chloro-3-Nitro-
CAS No.	918519-53-6
Molecular Formula	C7H4ClN3O2
Molecular Weight	197.58 g/mol
Synonyms	4-Chloro-3-nitro-1H-pyrrolo[2,3-b]pyridine; 4-Chloro-3-nitropyrrolo[2,3-b]pyridine; 3-Nitro-4-chloro-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 4-chloro-3-nitro-; 4-Chloro-3-nitro-7-azaindole; 7-Azaindole, 4-chloro-3-nitro-; 4-Cl-3-NO2-7-azaindole; 918519-53-6
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine, 4-Chloro-3-Nitro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.