Description

1H-Pyrrolo[2,3-B]Pyridine-4-Carbonitrile, 3-(2-Thienylthio)- is a high-value heterocyclic organic compound featuring a fused pyrrolopyridine core functionalized with a nitrile group and a thienylthio substituent. This specific molecular architecture makes it a critical advanced pharmaceutical intermediate for the research and development of novel active ingredients. It is primarily sought by pharmaceutical R&D organizations and fine chemical manufacturers engaged in the synthesis of complex molecules for therapeutic applications.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, particularly in kinase inhibitor research.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products.
• Material Science Precursor: Acts as a starting material for the synthesis of specialized organic ligands and functional polymers.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and the exploration of new chemical entities.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine-4-Carbonitrile, 3-(2-Thienylthio)-
CAS No.	918513-05-0
Molecular Formula	C12H7N3S2
Molecular Weight	257.33 g/mol
Synonyms	3-(Thiophen-2-ylthio)-1H-pyrrolo[2,3-b]pyridine-4-carbonitrile; 3-(2-Thienylthio)-1H-pyrrolo[2,3-b]pyridine-4-carbonitrile; 1H-Pyrrolo[2,3-b]pyridine-4-carbonitrile, 3-(2-thienylthio)-; 918513-05-0; 3-(Thiophen-2-ylsulfanyl)-1H-pyrrolo[2,3-b]pyridine-4-carbonitrile
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP-compliant manufacturing for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.