Description

2-Amino-5-Fluoro-3-Nitro-4-Picoline is a high-value, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its unique structure, featuring amino, fluoro, and nitro substituents on a picoline core, makes it a versatile precursor for creating complex molecular architectures. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates. Its reliable quality and consistent supply are critical for accelerating innovation in drug discovery and crop protection.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for targeted therapies.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and insecticides, leveraging its fluorine and nitro groups.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science Precursor: Potential use in the development of specialty chemicals, dyes, and advanced organic materials.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity intermediates.

Basic Information

Product Name	2-Amino-5-Fluoro-3-Nitro-4-Picoline
CAS No.	917918-86-6
Molecular Formula	C6H6FN3O2
Molecular Weight	171.13 g/mol
Synonyms	4-Picoline, 2-amino-5-fluoro-3-nitro-; 2-Amino-5-fluoro-3-nitropyridine-4-methyl; 5-Fluoro-2-amino-3-nitro-4-methylpyridine; 4-Methyl-2-amino-5-fluoro-3-nitropyridine; 2-Amino-3-nitro-5-fluoro-4-picoline; 3-Nitro-2-amino-5-fluoro-4-methylpyridine; 5-Fluoro-3-nitro-2-amino-4-picoline
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-5-Fluoro-3-Nitro-4-Picoline is manufactured under strict quality management protocols. Our products undergo rigorous quality testing, including HPLC for purity and identity confirmation, to ensure compliance with industry standards and customer-specific requirements. Certificates of Analysis (COA) documenting all critical parameters are available upon request, providing full traceability and assurance for your R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its light-sensitive nature and potential for oxidation, it is recommended to handle under an inert atmosphere for long-term storage and to minimize headspace in opened containers.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.