Description

7-Bromo-3-Chloro-5H-Benzo[4,5]Cyclohepta[1,2-B]Pyridin-5-One is a high-purity, advanced pharmaceutical intermediate characterized by its complex fused-ring heterocyclic structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of complex drug candidates, especially kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis Building Block: Employed in advanced organic reactions, such as cross-coupling and cyclization reactions, to construct more complex molecular architectures.
• Contract Research & Development (CRO/CMO): Supplied to contract research and manufacturing organizations supporting global pharmaceutical innovation.
• Academic Research: Utilized in university and institutional labs for fundamental research in heterocyclic chemistry and synthetic methodology development.

Basic Information

Product Name	7-Bromo-3-Chloro-5H-Benzo[4,5]Cyclohepta[1,2-B]Pyridin-5-One
CAS No.	917878-65-0
Molecular Formula	C14H7BrClNO
Molecular Weight	320.57 g/mol
Synonyms	7-Bromo-3-chloro-5H-benzo[4,5]cyclohepta[1,2-b]pyridin-5-one; 7-Bromo-3-chloro-5H-dibenzo[a,d]cyclohepten-5-one fused with pyridine; 5H-Benzo[4,5]cyclohepta[1,2-b]pyridin-5-one, 7-bromo-3-chloro-; 7-Bromo-3-chloro-dibenzocycloheptenone pyridine fused analog
EINECS	Contact for details

Quality Control

Our 7-Bromo-3-Chloro-5H-Benzo[4,5]Cyclohepta[1,2-B]Pyridin-5-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under dry, inert conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.