Description

3-Bromo-5-(Prop-1-Ynyl)Pyridine is a versatile and high-value halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a bromine substituent and an alkyne functional group, makes it a key intermediate for constructing complex molecules through cross-coupling and cycloaddition reactions. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and material science industries, enabling the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a monomer or functionalization agent in the creation of conductive polymers, liquid crystals, and metal-organic frameworks (MOFs).
• Chemical Synthesis: Employed in Sonogashira, Suzuki, and other palladium-catalyzed cross-coupling reactions to introduce the pyridyl-alkyne moiety into target molecules.
• Ligand Synthesis: Useful for preparing novel nitrogen-containing ligands for catalysis and coordination chemistry.
• Life Science Reagents: Incorporated into probes, tags, and molecular tools for biochemical and diagnostic applications.

Basic Information

Item	Details
Product Name	3-Bromo-5-(Prop-1-Ynyl)Pyridine
CAS No.	917772-69-1
Molecular Formula	C8H6BrN
Molecular Weight	196.05 g/mol
Synonyms	3-Bromo-5-prop-1-ynylpyridine; 5-(Prop-1-yn-1-yl)-3-bromopyridine; 3-Bromo-5-(1-propynyl)pyridine; 3-Bromo-5-propynylpyridine; 3-Bromo-5-ethynylpyridine (common misnomer); Pyridine, 3-bromo-5-(1-propynyl)-; 917772-69-1 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-5-(Prop-1-Ynyl)Pyridine is produced and tested under strict quality management protocols to ensure consistency and reliability for your research and development processes. Our products undergo rigorous quality testing, including chromatographic purity analysis and identity confirmation, to ensure compliance with industry standards. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.