Description

Lorediplon CAS NO 917393-39-6 is a non-benzodiazepine hypnotic agent belonging to the pyrazolopyrimidine class of compounds. This pharmaceutical intermediate is of significant interest for its role in the research and development of novel therapeutics targeting sleep disorders. It is primarily utilized by pharmaceutical R&D laboratories and manufacturers engaged in the synthesis of active pharmaceutical ingredients (APIs) for clinical studies and production.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of the active pharmaceutical ingredient (API) Lorediplon.
• Sleep Disorder Research: Critical material for preclinical and clinical research programs focused on developing new treatments for insomnia.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Process Chemistry Development: Used in scaling up and optimizing synthetic routes for GMP manufacturing.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for API production under cGMP guidelines.

Basic Information

Product Name	Lorediplon
CAS No.	917393-39-6
Molecular Formula	C₁₅H₁₅ClN₄O₂
Molecular Weight	318.76 g/mol
Synonyms	Lorediplon; (S)-N-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetamide; UNII-6G0V8BZ61P; 6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide, N-[4-(4-chlorophenyl)-2,3,9-trimethyl-; S-n-(4-(4-chlorophenyl)-2,3,9-trimethyl-6h-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetamide
EINECS	Contact for details

Quality Control

Our Lorediplon is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical R&D. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling. A Certificate of Analysis (COA) detailing all specifications and results is provided with every shipment. We support development needs with material produced in compliance with ICH Q7 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.