Description

Ethyl 3-(3-Fluorophenyl)-5-Methylisoxazole-4-Carboxylate is a high-purity fluorinated isoxazole derivative, a crucial advanced intermediate in modern organic synthesis. Its value lies in providing a versatile, functionalized scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluorinated isoxazole moiety.
• Material Science Precursor: Serves as a monomer or functional additive in the research of advanced polymers and liquid crystals.
• Chemical Biology Probe: Utilized in medicinal chemistry to study enzyme inhibition and receptor-ligand interactions due to its specific structural features.
• Custom Synthesis & Contract Manufacturing: A critical starting material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.
• Academic Research: Employed in university and institutional labs for methodological studies in heterocyclic and fluoroorganic chemistry.

Basic Information

Product Name	Ethyl 3-(3-Fluorophenyl)-5-Methylisoxazole-4-Carboxylate
CAS No.	917388-62-6
Molecular Formula	C13H12FNO3
Molecular Weight	249.24 g/mol
Synonyms	Ethyl 5-Methyl-3-(3-fluorophenyl)-1,2-oxazole-4-carboxylate; 4-Isoxazolecarboxylic acid, 3-(3-fluorophenyl)-5-methyl-, ethyl ester; 3-(3-Fluorophenyl)-5-methylisoxazole-4-carboxylic acid ethyl ester; Ethyl 3-(3-fluorophenyl)-5-methyl-4-isoxazolecarboxylate; 917388-62-6; 5-Methyl-3-(3-fluorophenyl)isoxazole-4-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 3-(3-Fluorophenyl)-5-Methylisoxazole-4-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.