Description

(R)-1-tert-Butyl2-Ethyl5-Oxopiperidine-1,2-Dicarboxylate CAS NO 917344-15-1 is a high-purity chiral piperidone derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a stereochemically defined scaffold for constructing complex pharmaceutical intermediates and fine chemicals. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require high-quality, enantiomerically pure starting materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Asymmetric Synthesis: Utilized as a precursor for catalysts or ligands in stereoselective reactions due to its defined (R)-configuration.
• Peptidomimetic Research: Serves as a constrained scaffold in the design and development of peptide analogs and protease inhibitors.
• Agrochemical Development: Employed in the research phase for creating novel, enantiomerically pure active ingredients for crop protection.
• Academic & Industrial R&D: Used in methodological development and exploration of new synthetic pathways in organic chemistry laboratories.
• Fine Chemical Production: Acts as a building block for the manufacture of specialty chemicals requiring specific stereochemistry.

Basic Information

Item	Detail
Product Name	(R)-1-tert-Butyl2-Ethyl5-Oxopiperidine-1,2-Dicarboxylate
CAS No.	917344-15-1
Molecular Formula	C14H23NO5
Molecular Weight	285.34 g/mol
Synonyms	(R)-1-(tert-Butoxycarbonyl)-2-ethoxycarbonyl-5-oxopiperidine; (R)-1-Boc-2-(COOEt)-5-oxopiperidine; (3R)-3-[(Ethoxycarbonyl)amino]-5-oxopiperidine-1-carboxylic acid tert-butyl ester; (R)-1-tert-Butyl 2-ethyl 5-oxopiperidine-1,2-dicarboxylate; tert-Butyl (R)-2-(ethoxycarbonyl)-5-oxopiperidine-1-carboxylate; (R)-N-Boc-N-(ethoxycarbonyl)-5-oxopiperidine; 1,2-Piperidinedicarboxylic acid, 5-oxo-, 1-(1,1-dimethylethyl) 2-ethyl ester, (2R)-
EINECS	Contact for details

Quality Control

Our (R)-1-tert-Butyl2-Ethyl5-Oxopiperidine-1,2-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC, to ensure high enantiomeric purity and chemical identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The compound is light-sensitive; containers should be opaque or stored in darkness.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.